Frequently Asked Questions

Product FAQs

What does BLIS stand for? 

Glad you asked! BLIS is an acronym for Bacteriocin-Like Inhibitory Substances - and the core of our science and advanced probiotics. 

What, then, is an advanced probiotic?

Probiotics are good bacteria that have been characterized for their beneficial properties. They work by rapidly reproducing and crowding out any bad bacteria. You might be familiar with probiotics aimed to maintain a good balance in the gut, but your gut is not the only place that has has a biome worth keeping in balance.

Advanced probiotics are slightly different in that they also provide the benefit of producing bacteriocins (small proteins) that are inhibitory against other bacteria species. So, not only do they crowd out the bad bacteria, they inhibit them with bacteriocins.

However, not all probiotic strains can do this. BLIS K12™ and BLIS M18™ are both advanced probiotics strains that utilise Streptococcus Salivarius, which means that they have this additional capability.


Streptococcus salivarius is a species of spherical, gram-positive, facultative anaerobic bacteria that is both catalase and oxidase negative. S. salivarius colonizes (usually in chains) the mouth and upper respiratory tract of humans just a few hours after birth, making further exposure to the bacteria harmless in most circumstances.

Some strains of S. salivarius are marketed as a probiotic for oral health. Some strains of S. salivarius are found to produce BLIS (the above-mentioned bacteriocin-like inhibitory substances) which are peptides that display interspecies inhibition.

BLIS K12® and BLIS M18® are both specific strains of Streptococcus salivarius and the core of our oral probiotics.

What are oral probiotics and how do they differ from other probiotics?

As noted, most probiotics are targeted towards the gut and digestive tract.

Oral probiotics, however, are those that support the mouth and throat, protecting the oral cavity (a fancy way of saying mouth, teeth, gums and throat).

BLIS K12™ probiotics populate the mouth and throat with good bacteria, crowding out the bad. In science terms – this is known as ‘bacterial interference’.

By creating a forcefield, oral probiotics can support mouth and throat health. BLIS K12™ is also used in our FreshBreath kits which restore the balance of good bacteria to the oral cavity and can aid bad breath and halitosis.

BLIS M18® works in a similar way but it is targeted specifically at the bad bacteria that can cause teeth and gum issues.

What is the benefit of taking an oral probiotic?

In an ideal world, everybody would have the right balance of microbes in their oral cavity. Unfortunately, this is not the case for most people, as only a small portion of the population (about 2%) already have the natural presence of BLIS-producing Streptococcus salivarius.

For the rest of us, taking a BLIS probiotic regularly will boost the oral cavity with these healthy bacteria and support good oral health. 

Is it true that the active ingredient in both ThroatGuard PRO / DailyDefence and FreshBreath is the same? If so, why do I need to purchase both products? And if so, is it safe?

The lozenges in our ThroatGuard PRO, DailyDefence and FreshBreath kits are the same – BLIS K12™.

However, for people who suffer from bad breath (halitosis), it is important they use the antibacterial mouthwash and tongue scraper as directed.

The FreshBreath Kit is a specifically designed solution which works to remove the bacterial layer that forms on the mouth, and then aims to repopulate the oral cavity with good bacteria.

I’ve been using the FreshBreath Kit for several months now and I’m experiencing fantastic results. Should I continuously use it all the time, or take a break for a while?

We’ve found that continuing to use the FreshBreath Kit achieves long-term sustained fresh breath, which supports it being a part of your regular dental hygiene routine.

We know that there is some ongoing effect when taking BLIS K12™ but it does drop off if not maintained, so using one FreshBreath Kit will not stop bad breath forever.

My child has strep throat and is currently on antibiotics. Should I start him on BLIS Probiotics now or wait until he has finished the antibiotics?

We would recommend beginning BLIS Probiotics the day after the course of antibiotics is complete.

It is important to take the full course of antibiotics as they will kill off the bad bacteria that is causing the infection. But, the way antibiotics work is that they also kill the ‘good’ bacteria, which means that if you're taking BLIS products at the same time as antibiotics, the beneficial effects of BLIS won't be as strong. 

The optimal time to recolonize the oral cavity with good bacteria (BLIS K12® or BLIS M18®) is immediately following the course of antibiotics.

Is it okay to take BLIS Probiotics straight after food or cleaning teeth?

You can take your daily lozenges whenever is most suitable, and up to 4 lozenges a day.

However, for optimal results during the day, it is best not to eat or drink at least 30 minutes after taking the lozenge.

At night, you should take the lozenge after brushing your teeth.

Will BLIS K12™ or BLIS M18™ help with recurring mouth ulcers?

We have not conducted any trials in this area yet so we are unable to say if this is an area that BLIS Probiotics can be utilized for.

What is the best form of BLIS K12™ and BLIS M18™? Lozenges? Gum? Powder?

We typically produce BLIS K12® and BLIS M18® in lozenge form as it is the most effective way to colonise the mouth and throat with the good bacteria. 

Allowing the lozenge to dissolve slowly on the tongue gives it the best opportunity to work its magic in the mouth and throat area.

We also offer a powdered form which is suitable for children who may struggle to suck on a lozenge.

It's important to note that the lozenge should not be swallowed whole as that will lead to no beneficial colonisation in the mouth. And, it should not be chewed, as that will cause the good bugs to die before they can do their work.

What is the bacteria count for your products?

We measure the bacteria count in CFU: colony forming units at the date of manufacture.

ToothGuard and ToothGuard Junior (BLIS M18™) contain 2.50 billion CFU/dose.

ThroatGuard PRO (BLIS K12™) contains 2.50 billion CFU/dose.

DailyDefence (BLIS K12™) contains 1.25 billion/dose.

TravelProtect (BLIS K12™) contains 1.5 billion CFU/dose.

DailyDefence Junior (BLIS K12™) contains 1.25 billion CFU/dose.

HoneyBlis (BLIS K12™) contains 1.0 billion CFU/dose.

Can BLIS K12™ and BLIS M18™ be taken together?

We recommend that while you can take both BLIS K12® and BLIS M18® in the same day, you should separate when you take the lozenges to get optimum benefit from each strain.

Our recommendation is that you take BLIS M18® at night and BLIS K12® in the morning. We don't recommend both lozenges are taken together or immediately after each other.

How does BLIS TravelProtect work?

By taking a high dose over a short intense timeframe, you can boost your natural immune defences.

The dosage of BLIS K12™ in TravelProtect is enough to support this response so that you have additional protection from bad bacteria.

This is particularly relevant when travelling on airplanes as there are a lot of airborne germs filtering through the airplane air-conditioning system.

I’ve seen other branded products that contain BLIS K12™. Is this the same BLIS probiotic?

Our company, BLIS Technologies Limited, has the world-wide patent for both the BLIS K12® and BLIS M18® strains. We produce our own finished goods which are available here, online, and in New Zealand pharmacies.

We also supply ingredients to manufacturers who sell and distribute in overseas markets. If another brand is correctly displaying the BLIS trademarks and patent statements, it is likely that they have been supplied genuine BLIS K12® or BLIS M18®.

If you are concerned about a product being ‘real’, look for reference to BLIS Technologies and the strain that the product contains. Any product that includes our active ingredients need to correctly label their packaging and reference both the company and the strain name.

And, if still in doubt, you can also reach out to us via email or social media and we can help advise further. 

Do BLIS probiotics contain sugar or gluten?

All Blis probiotics are sugar-free and gluten-free.

How should I store my BLIS probiotics?

We recommend storing BLIS Probiotics below 25 degrees Celsius. They are shelf-stable so they do not need to go into the fridge.

Are BLIS probiotics safe to take alongside other medications?

While you shouldn’t incur problems taking a BLIS probiotic alongside other prescription medication, you should seek the advice from your physician. If you are taking antibiotics you should complete the antibiotics before starting to take BLIS Probiotics.

All BLIS probiotics are GRAS approved (Generally Recognised as Safe) by the United States Food and Drug Administration.

Are there any products that will interfere with BLIS K12™?

We do not recommend using BLIS Probiotics at the same time as taking antibiotics for any condition associated with the ears, nose, throat or mouth.

Anti-microbial mouthwash also kill off good and bad bacteria. If you use anti-microbial mouthwash – always take BLIS Probiotics as the last step in your dental hygiene routine.

Ordering & Shipping FAQs

Can I track my order?

We use NZ Post for shipping and they have this handy tracking site for finding out where your order is at.

Just enter the order number you received in your order confirmation email from us. We will also send you an email upon purchase with this information.

How long will my order take to arrive?

We aim to have orders processed and shipped within 24 hours of receiving them.

What international countries do you currently ship to? 

International Air (Air Parcel) – no tracking - $25.00 flat rate for orders under $249.99

(Estimated delivery: 20 business days)

Afghanistan, Albania, Algeria, Andorra, Angola, Anguilla, Antigua & Barbuda, Argentina, Armenia, Aruba, Azerbaijan, Bahamas, Bahrain, Bangladesh, Barbados, Belarus, Belize, Benin, Bermuda, Bhutan, Bolivia, Bosnia & Herzegovina, Botswana, British Indian Ocean Territory, Brunei, Bulgaria, Burkina Faso, Burundi, Cambodia, Cape Verde, Cayman Islands, Chad, Christmas Island, Cocos (Keeling) Islands, Comoros, Congo - Brazzaville, Cuba, Cyprus, Côte d’Ivoire, Djibouti, Dominica, Dominican Republic, Egypt, Equatorial Guinea, Eritrea, Ethiopia, Falkland Islands, Faroe Islands, French Guiana, French Polynesia, French Southern Territories, Gabon, Gambia, Georgia, Ghana, Greenland, Grenada, Guadeloupe, Guatemala, Guernsey, Guinea, Guinea-Bissau, Guyana, Haiti, Vatican City, Honduras, Iran, Iraq, Isle of Man, Israel, Jamaica, Jersey, Jordan, Kazakhstan, Kenya, Kiribati, Kuwait, Kyrgyzstan, Lebanon, Lesotho, Liberia, Liechtenstein, North Macedonia, Malawi, Maldives, Mali, Martinique, Mauritania, Mayotte, Moldova, Monaco, Mongolia, Montenegro, Montserrat, Morocco, Mozambique, Myanmar (Burma), Namibia, Nauru, Nepal, Netherlands Antilles, Nicaragua, Niger, Nigeria, Niue, Norfolk Island, Oman, Pakistan, Palestinian Territories, Panama, Papua New Guinea, Paraguay, Peru, Qatar, Cameroon, Réunion, Rwanda, St. Helena, San Marino, Senegal, Seychelles, Sierra Leone, Solomon Islands, Sudan, Suriname, Tanzania, Timor-Leste, Togo, Tokelau, Trinidad & Tobago, Tunisia, Turkmenistan, Turks & Caicos Islands, Tuvalu, Uganda, Ukraine, United Arab Emirates, Uzbekistan, Venezuela, British Virgin Islands, Wallis & Futuna, Yemen, St. Kitts & Nevis, St. Lucia, St. Pierre & Miquelon, Saudi Arabia


International Courier – Track & Trace - $60.00 Flat Rate for orders under $249.99

(Estimated delivery: 7-10 business days)

Fiji, Indonesia, Japan, Macao SAR, Philippines, Taiwan, Cook Islands, New Caledonia, Samoa, Thailand, Tonga, Vanuatu, Vietnam


International Courier – Track & Trace - $65.00 flat rate for orders under $249.99

(Estimated delivery: 7 – 10 business days)

Chile, Costa Rica, Ecuador, El Salvador, Sri Lanka, Uruguay, Czechia, France, Greece, Hungary, India, Romania


International Tracked Satchel – Track & Trace - $30.00 Flat rate for orders under $249.99

(Estimated delivery: 7-14 business days)


International Courier – Track & Trace - $65.00 flat rate for orders between $250.00 - $499.00 (Estimated delivery: 7 – 10 business days)

Iceland, Ireland, Latvia, Malaysia, Malta, Mauritius, Mexico, Norway, Portugal, Russia, Serbia, South Korea, Switzerland, Turkey, Austria, Belgium, Croatia, Denmark, Estonia, Finland, Sweden, Hong Kong SAR, Italy, Lithuania, Luxembourg, Netherlands, Poland, Singapore, Slovakia, Slovenia, Spain, United Kingdom, Germany, China, Brazil



(But….You can buy BLIS Products on Amazon US and Amazon Canada, respectively.)


Sorry, we’re currently not shipping to the following countries:

Åland Islands, Ascension Island, Bouvet Island, Canada, Caribbean Netherlands, Central African Republic, Colombia, Congo - Kinshasa, Curaçao, Eswatini, Gibraltar, Heard & McDonald Islands, Kosovo, Laos, Libya, Madagascar, New Zealand (1 of 17 regions), Pitcairn Islands, São Tomé & Príncipe, Sint Maarten, Somalia, South Africa, South Georgia & South Sandwich Islands, South Sudan, St. Barthélemy, St. Martin, St. Vincent & Grenadines, Svalbard & Jan Mayen, Tajikistan, Tristan da Cunha, U.S. Outlying Islands, United States (56 of 62 states), Western Sahara, Zambia, Zimbabwe

How much does delivery cost?

New Zealand 

$5.00 Flat rate for orders under $80.00 (NZ Post Overnight with Track & Trace, rural areas will take longer) 

FREE Shipping for orders over $80.00 (NZ Post Overnight with Track & Trace, rural areas will take longer) 



 $15.00 Flat Rate for orders under $80.00 (NZ Post Tracked Satchel, with track & trace)

(Estimated delivery: 7-14 business days) 

FREE Shipping for orders over $80.00 - $249.99 

(NZ Post Tracked Satchel, with track & trace)

(Estimated delivery: 7-14 business days) 

FREE Shipping for orders over $250.00 (NZ Post International Courier with track & trace)­

(Estimated delivery: 5-7 business days) 


Rest of the world

Please refer to the section above.

Please note that customers are responsible for the settlement of any customs tax/duties imposed in their respective countries.

Can I change or cancel my order once I've placed it?

To change your order please email as soon as possible.  We will endeavour to help but it is dependent on whether the order has already been shipped.

Once shipped, we can’t change the order. Please refer to our Refund Policy for more information.


Missing or Damaged Goods

If your product was damaged in transit please send a photo to us at

On confirmation of the damage, we will send you a replacement product with a pre-paid courier bag included for you to return the damaged goods to us.

For missing items, we recommend trying Track & Trace first, and checking with neighbours. If this doesn’t track down your parcel then contact us and we will investigate with the shipping provider from this end.

Can you give medical advice?

While we have a world-class science and microbiology team, we are unable to provide you with medical advice. We can however provide detailed information on product-related queries. You should seek any medical advice from your doctor.

Do you offer any discount for bulk purchases?

We recommend you create an account with Blis Technologies, that way you can hear about any special promotions that Blis is offering exclusively to online customers. As a standard practice, we do not offer discount for bulk purchases through our online store.

If you wish to enquire about that you can email us:

Where are your products manufactured?

We are proud to be a New Zealand based company. From research and development, through to manufacturing and packaging, Blis Technologies does it all from our headquarters in Dunedin.

What are the online payment options?

We offer two payment methods for online orders: major credit cards VISA and MasterCard; or PayPal.

Can I still purchase online if I don’t have a credit card or PayPal?

Payment through our online portal is the fastest and easiest way to receive your order. Our online system requires VISA, MasterCard or PayPal. But if these payment options don’t suit you, please get in touch with our customer service team and we’ll see if we can come up with another arrangement!

Are your online prices consistent with those in retail shops?

Our online prices are consistent with recommended retail prices (RRP) for shops and pharmacies.