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BLIS Technologies are the developers of the world’s first advanced oral probiotics. We call them "advanced probiotics" because they not only crowd out the bad stuff but also inhibit them from coming back when they are under threat.

Certain types of bacteria also naturally produce additional substances made of peptides and proteins that inhibit the bad bacteria from coming back.

These proteins are called Bacteriocin-Like Inhibitory Substances (BLIS) and it is the inspiration for our company name and our patented strains.

Our probiotics products have been extensively safety-tested and have been commercially used for more than 15 years. Streptococcus salivarius is the dominant organism in a healthy oral cavity. It’s found in breast milk and is listed as a Biosafety Level 1 (safest) organism in the USA.

All our products are developed and manufactured at our laboratory in Dunedin, New Zealand. 

BLIS K12™ & BLIS M18™ Oral Probiotics

We currently market two strains of probiotic bacteria – BLIS K12™ and BLIS M18™ – both of which occur naturally in the oral cavity. However, only around 2% of the population have these healthy bacteria at levels high enough to be effective.

BLIS K12™ was our first discovery. It was originally developed into a probiotic supplement to support throat health, but the benefits of BLIS K12™ have been found to be more wide-reaching as more studies have been completed. We know that BLIS K12™ also supports the ear, nose and throat health of infants and children, and is also effective in improving bad breath (halitosis).

The second strain – BLIS M18™ – was discovered later and this promotes the healthy bacterial balance for dental health. 

 World's first Oral Probiotics

BLIS Q24® Probiotic Skincare

Our most recent commercially available strain, BLIS Q24®, is the name for the unique probiotic strain found in Unconditional Skincare Co. products, and a bit less of a mouthful than its scientific name, Micrococcus luteus Q24. The strain naturally occurs on human skin - so it’s perfectly suited to thrive in your skin microbiome.

BLIS Q24 Skin Probiotic

The BLIS Product Portfolio

DailyDefence – a daily advanced probiotic containing BLIS K12™ to support throat immunity.

DailyDefence Oral Probiotics

DailyDefence Junior – a daily powder formulation of BLIS K12™ to support ear, nose and throat health of infants and small children.

Daily Defence Junior Kids Probiotics

ElitePRO – our WADA tested products for high performance athletes, developed in collaboration with High Performance Sport NZ (

Elite Pro Sports Probiotics

ThroatGuard PRO - a high dose of BLIS K12™ to give boosted immunity support to help protect against winter ills.

ThroatGuard Oral Probiotics

TravelProtect – a higher dose formulation of BLIS K12™ with a specialised regimen to help support the immune system when travelling.

Travel Protect Oral Probiotics

FreshBreath Kit – a regime that re-populates the mouth with BLIS K12™, thereby replacing the bad ‘smelly’ bacteria in the mouth, not simply masking it.

Fresh Breath Oral Probiotics to fight bad breath

HoneyBlis and HoneyBlis Ginger – a great tasting honey lozenge with BLIS K12™ to soothe and protect a scratchy or dry throat.

HoneyBlis Oral Probiotics for sore throat

UltraBLIS – A unique combination of probiotic strains that support the oral and the gut microbiomes.

UltraBLIS Oral Probiotics for immunity

ToothGuard and ToothGuard Junior – our advanced probiotic with BLIS M18™ for the health of teeth and gums, helping to prevent cavities in children and maintaining healthy gums in adults.

ToothGuard Dental Probiotics with BLIS M18